Resistin-like molecule (RELMβ)—a protein that is secreted from goblet cells after local tissue damage triggers a proinflammatory cytokine milieu, including IFN-γ and tumor necrosis factor-alpha (TNF-α)—is thought to be driving the Th1 immune infiltration, leading to the chronic colonic pathology in both trichuriasis and IBD [41,42]. This evidence concerns the gene TNF and inflammatory bowel disease.