In multivariate analysis taking into account gender, age, T status, LNR, adjuvant therapy, tumour size, resection radicality, CA19-9, CEA, and GPS, a score of GPS 1 was not significantly associated with survival, whereas GPS 2 raised the HR significantly to 2.2 compared to HR for GPS 0 (p = 0.001) (Table 5). Here, CEACAM5 is linked to neoplasm.