In 1985, Ishikura et al[9] first described hepatoid adenocarcinoma, which showed a histologic appearance typical of HCC, including solid, trabecular, and pseudogranular structure; tumor cells were round or polygonal in shape.[10] Different with above 2 kinds of gastric cancer, our patient's feature was just with serum AFP elevation. The gene discussed is AFP; the disease is hepatoid adenocarcinoma.