ACE and gastroesophageal reflux disease: GERD frequently leads to chronic laryngitis;[39–42] however, there are some differences in the mechanism of diseases, and these changes may also appear secondary to smoking, excessive alcohol, allergies, asthma, or voice abuse.[37,42] Fourth, medication effects, such as those of angiotensin-converting enzyme inhibitors, were not evaluated since most participants did not know the exact name of their prescribed medication.