To determine the impact and the role of miR-196a in HD pathogenesis, a panel of genes related to HD (HTT, Huntingtin-interacting protein 1:HIP-1), apoptosis (Annexin1A: ANX1A) and neural cell growth (BDNF) were quantitatively measured by qPCR in NPCs and NCs. This evidence concerns the gene HIP1 and Huntington disease.