Maternal HIV infection was associated with decreased levels of cord IgG1 and IgG3 against MSP1 and lysate, with cord IgG1 against apical membrane antigen 1 (AMA1), and with cord IgG3 against EBA175. Maternal HIV infection was associated with reduced transfer of IgG1 against AMA1, of IgG1 and IgG3 against lysate, and of IgG3 against MSP1 and EBA175 (48). Here, IGHG3 is linked to HIV infectious disease.