In humans, mutations in PLA2G6 lead to a spectrum of hereditary disorders classified as neurodegeneration with brain iron accumulation (NBIA) (15), infantile neuroaxonal dystrophy (INAD) (16), adult dystonia-parkinsonism (17), and Parkinson disease (18). This evidence concerns the gene PLA2G6 and neurodegeneration with brain iron accumulation 2A.