The JAK/STAT signaling pathway is a primary target of Gas6 signaling (Yanagita et al., 2001) and has been shown to promote oligodendrocyte regeneration and remyelination (Hesp et al., 2015), as well as being a promising therapeutic target in multiple animal models of MS (Liu et al., 2014). Here, SOAT1 is linked to myeloid sarcoma.