TP53 and cancer: The WT canonical p53 protein (TAp53α) prevents cancer invasion by inhibiting EMT (Gadea et al., 2007; McDonald et al., 2011; Muller et al., 2011; Roger et al., 2010; Suva et al., 2013) while the mutant canonical p53 protein (mutant TAp53α) was shown to promote cell invasion (Adorno et al., 2009; Gadea et al., 2002, 2004; Muller et al., 2009; Roger et al., 2010; Gadea et al., 2007).