Importantly, Δ133p53β expression was also associated with cancer progression in WT TP53 breast cancer patients (Kaplan-Meier log-rank test, CP: χ2 = 5.232, p≤0.022) (Figure 1—figure supplement 1I), indicating that the association between ∆133p53β expression and cancer progression is not due to TP53 mutation. This evidence concerns the gene TP53 and cancer.