To clarify the univariate analyses and adjust for possible confounding variables, the association of overall survival and disease-free survival with Δ133p53β, the breast cancer subtypes (luminal-A, luminal-B, HER2+, triple-negative and luminal/HER2+), TP53 mutation, tumor grade, lymph node metastasis and/or tumor size (>20 mm) were investigated using the multivariate Cox’s regression analysis. The gene discussed is ERBB2; the disease is metastatic malignant neoplasm in the lymph nodes.