However, pyrexia and CG2678 show a clear regulation at the post-transcriptional level as the expression of pre-pyx and pre-CG2678 do not change significantly in dis3L2 knockdown discs compared to controls, but increase in expression by 2.4 and 2.1-fold respectively at the mRNA level (Fig. 6B and Table 1). This evidence concerns the gene DIS3L2 and Fever.