IL18 and acute kidney injury: Recently, several promising urinary protein biomarkers have been proved to be remarkably helpful for detecting AKI, such as Calprotectin, neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, interleukin-18 (IL-18), kidney injury molecule-1 (KIM-1), and L-type or liver-type fatty acid-bind protein (LFABP) [2, 21–24].