In this scenario, the visualisation of the communication between the BD-IPMN and the pancreatic duct system is a key feature that allows us to distinguish IPMNs from cystic lesions of other aetiologies. MRCP uses the almost stationary fluid in the biliary and pancreatic ductal system as an intrinsic contrast medium that can be improved in the detailed evaluation of the biliary and pancreatic ductal anatomy of IPMN by administration of secretin [2, 12, 23]. This evidence concerns the gene SCT and pancreatic intraductal papillary-mucinous neoplasm.