Furthermore, our own qRT-PCR data confirmed the up-regulation of CRNDE, NR_036488, ENSG00000244649, AFAP1-AS1, UCA1 and down-regulation of ENSG00000218510 in PDAC and the subsequent analysis of their correlations with clinicopathological features and prognosis also indicated that part of them such as up-regulated AFAP1-AS1, UCA1 and down-regulated ENSG00000218510 may contribute to tumor progression and predict unfavourable prognosis in PDAC patients. The gene discussed is AFAP1; the disease is neoplasm.