For instance, α-eleostearic acid potently inhibited the growth of HT-29 colon cancer cells36 and conjugated linolenic acid induced apoptosis by reducing the expression of Bcl-2 with corresponding increase in the expression of GADD45, p53 and PPARγ in Caco-2 colon cancer cells37. This evidence concerns the gene TP53 and malignant colon neoplasm.