The independent predictors of paroxysmal AF compared with SR were heart failure [OR 9.1, 95%CI 3.7, 22.5, p<0.001] and age [OR 1.6 per decade, 95%CI 1.1, 2.5, p = 0.028], while C-reactive protein did not reach statistical significance. The gene discussed is CRP; the disease is Paroxysmal atrial fibrillation.