The ORs of CHD forsubjects in the second and first (lowest) tertile of mean IL-6 methylation were1.87 (95% CI = 1.10-3.20) and 2.01 (95% CI = 1.19-3.38) (ptrend =0.013), respectively, compared to individuals in the third (highest) tertile.When evaluated by clinical types of CHD, the IL-6 hypomethylation-related riskestimates tended to be stronger for AMI, with OR of 2.00 (95% CI = 3.2-5.2) forthe second tertile and 2.57 (95% CI = 1.33-4.95) for the first tertile(ptrend = 0.006, Table2). Here, IL6 is linked to coronary artery disorder.