PTEN protein levels in APL (n=28 samples, mean + SEM: 0.42 ± 0.42) were also significantly lower than that of other AML (n=30 samples, mean + SEM: 1.4 ± 0.6) (p<0.0001) (Figure 1b). The gene discussed is PTEN; the disease is acute myeloid leukemia.