No statistically significant effects on CD4+Foxp3− Teff cells, CD4+Foxp3+ Treg cells, CD3−NKp46+ NK cells or CD11b+Gr1+ myeloid cells were observed, and no effects were observed for any of these populations within spleens or tumor-draining inguinal lymph nodes (data not shown). Here, ITGAM is linked to neoplasm.