IKBKB and atopic eczema: To further elucidate whether the immune-suppressive effect of ILG on the T cell activation is the result of mediating Cys-46 of IKKβ in vivo, we generated IKKβC46A transgenic mice and conducted a delay-type hypersensitivity (DTH) experiment, a mouse inflammatory model for atopic dermatitis triggered by T cells.