To further elucidate the effect of miR-29a and gemcitabine combination on pancreatic cancer cell autophagy, miR-29a expressing Panc-1 and MIA PaCa-2 cells were treated with gemcitabine and subjected to LC3B and p62 western blot analysis (Supplementary Figure S9). Here, SQSTM1 is linked to familial pancreatic carcinoma.