AKT1 and malignant colon neoplasm: Combined inhibition and activation showed a higher activity of pS6, p4E-BP1, and pmTOR (p<0.01 after 24 hours) than sole Akt inhibition in the colon cancer cell lines HT29, HCT116 and SW480 (exception: SW480 cells showed a reverse 4E-BP1expression pattern, Supplementary Figure S3E)