SMYD3 and esophageal squamous cell carcinoma: According to the Oncomine database, SMYD3 is also overexpressed in esophageal squamous cell carcinoma, oral cavity squamous cell carcinoma, acute myeloid leukemia, pancreatic ductal adenocarcinoma, leiomyosarcoma and renal Wilms' tumor (Supplementary Figure S2).