Interestingly, data extracted from TCGA displayed a statistically significant correlation between PROX1 gene expression and survival for patients with IDH-mutant, 1p19q non-codeleted low-grade astrocytomas, but not with IDH-wildtype or 1p19q codeleted low-grade gliomas (Supplementary Figure 1). This evidence concerns the gene PROX1 and glioma.