Much higher concentrations of Rhiz were needed to effectively reduce Kv1.3-mediated currents (Figure 4D, 4E), and the inhibition of herg1 channels (also found in prostate cancer cells [17], but an undesired target in cardiopharmacology [18]) was weaker than the one observed for heag1 (Figure 4F). Here, KCNH1 is linked to Familial prostate cancer.