The tumor cell proliferation and vascularity, which were evaluated by KI-67 and CD34, respectively, were markedly decreased in BCAT1 sh#1 rats than IDH1 WT rats (5.48% [IQR,–0.04–11.00] vs 33.86% [23.56–44.18]; p = 0.0001, and 1.22% [IQR, 0.71–1.72] vs 5.20% [2.44–7.95]; p = 0.0044, respectively). Here, IDH1 is linked to neoplasm.