Of note, downregulation of NQO1 was found in follicular lymphoma and Burkitt’s lymphoma [45] and, in a series of three lymphoma cell lines, under-expression of NQO1 transcription was shown to correlate with decreased sensitivity to the chemotherapeutic agents: mitomycin C, fluorouracil, and benzoquinone ansamycins e.g. geldanamycin. This evidence concerns the gene NQO1 and Burkitt lymphoma.