In contrast to the impaired capillary supply, the expression of VEGFs and VEGF receptors were not reduced in malignant hypertension, with the exception of myocardial VEGF A. Some renal VEGF isoforms and plasma VEGF levels were even higher in malignant hypertension than in non-malignant hypertension and controls. The gene discussed is VEGFA; the disease is malignant hypertension.