Expecting to provide insightful information regarding Connexin 43 expression as a biomarker for prostate cancer progression, we collected pathological specimens from 243 patients who underwent radical prostatectomy and from 60 benign prostatic hyperplasia (BPH) patients for tissue microarray construction and immunohistochemical analysis of Connexin 43 expression. Here, GJA1 is linked to prostate carcinoma.