To examine whether Wnt2 or Wnt3 expression is altered in response to fluoxetine treatment under CRS condition, mice were randomly assigned into three groups: No-CRS+saline (No-CRS+SAL), CRS+saline (CRS+SAL) and CRS+fluoxetine (CRS+FLX). The gene discussed is WNT2; the disease is congenital rubella syndrome.