Among the mRNAs targeted by differentially expressed miRNAs, there were several (Prkar1a, Rims2, Map2, Gabarapl1, Htr7, Add3, Erc1, Nlgn1) which were involved in synapse formation and function suggesting that synaptic function was one of the biological processes affected in form-deprivation myopia. The gene discussed is RIMS2; the disease is myopia.