Since many of these features are shared by Rodriguez/Nager syndrome cases, including cleft palate, micrognathia, and hypoplasia/absence of the radii and fibulae, the reduction of DLX5/6 expression that resulted from reduced SF3B4 expression likely contributes to these aspects of the phenotype as well. The gene discussed is DLX5; the disease is Nager acrofacial dysostosis.