Though PPARα, PPARβ/δ and PPARγ are ubiquitously expressed throughout the body [13, 14], PPARβ/δ has been shown to be involved in regulation of pathways important in AMD pathogenesis, including lipid metabolism, extracellular matrix remodeling, angiogenesis and inflammation [1, 15]. Here, PPARD is linked to age-related macular degeneration.