IFNL3 and chronic hepatitis C virus infection: Polymorphism in both IFN‐λ3 and KIRs synergize to predict the outcome of acute infection or response to IFN‐based therapies 19, 20 and altered NK cell effector functions in chronic hepatitis C were associated with IFN‐λ3 polymorphism 21 suggesting an active role for IFN‐λ3 in NK cell activation.