Many of these genes are known candidates for ASD, including DLX5 and DLX6 (reviewed above), FGFR2, MSX1, POLR1A, and PTCH1. Both DLX5 and DLX6 are indeed required for NC-derived facial morphogenesis (Gitton et al., 2011) FGFRs are among the main craniosynostosis-associated genes. Here, DLX6 is linked to craniosynostosis.