NFE2L2 and myeloid sarcoma: Nrf2-activating compounds, like sulforaphane (SFN) [33,34,35,36,37,38], fumaric acid esters [39,40,41,42], and Protandim® [43,44,45] are known to induce antioxidant enzymes in various cell types, have cytoprotective properties and reduce clinical signs in the experimental autoimmune encephalomyelitis animal model for MS.