TLR7 and actinic keratosis: Imiquimod (query 1) is a TLR7 agonist currently used for topical treatment of genital warts caused by human papillomavirus, actinic keratosis, and superficial basal cell carcinoma [177], and query 2 compound was developed in the last years in a systematic SAR exploration study as the most potent imidazoquinoline with TLR7 agonist activity [178].