CDC42 and neuroblastoma: In neuroblastoma, there is an increased fraction of cells in the G0/G1 phase at the expense of the S phase population in FOXP1-expressing cells, and induction of FOXP1 delayed cell cycle progression and upregulated pro-apoptotic genes such as DIABLO, CDC42, and DAPK1, indicating the induction of the intrinsic pathway of apoptosis [32].