Another intriguing example is given by the interference of the “oncochannel” ether-à-go-go-1 (EAG1) with the aberrant signaling in tumor cells: EAG1 is highly overexpressed in many tumor entities and sole transfection of Chinese hamster ovary cells with EAG1 (but not with a less oncogenic voltage gated Kv K+ channel type used for control) is sufficient to render CHO cells highly tumorigenic and malignant progressing when grown ectopically in immunocompromised mice [10]. This evidence concerns the gene KCNH1 and neoplasm.