To identify new autoantibodies in SSc, we first screened 9483 human proteins spotted on protein arrays with 20 sera from patients with SSc, including patients positive for ACA (ACApos), positive for ATA (ATApos) or negative for both antibodies (ATA/ACAneg) and 18 sera from controls (healthy and with other autoimmune diseases (AID)). Here, ATM is linked to systemic sclerosis.