TGFβ1 has been well documented to be associated with mesenchymal properties by breast cancers.13 However, it is rare that this cytokine alone is sufficient to induce EMT.47, 48 Our results indicated that the induction of the ZEB1-EPB41L5 axis by TGFβ1 does not always occur among different mammary epithelial cells. Here, TGFB1 is linked to breast cancer.