To this end, we analyzed the transcriptome data set of colorectal cancer provided by The Cancer Genome Atlas (TCGA) project.35 Given the functional link between ARHGEF5 and EMT in our in vitro observations, we also investigated the expression of E-cadherin (CDH1) and Snail (SNAI1) to stratify the patients. Here, SNAI1 is linked to colorectal cancer.