Anti-GFAP immunoreactivity was also enhanced 1 and 7 days after retinal ischemia in the rats pretreated with vehicle (Group 2 on I/R day 1, Fig. 4g; Group 2 on I/R day 7, Fig. 4p) compared with those in the control retina Group (sham 1 day, Fig. 4f; sham 7 days, Fig. 4o). This evidence concerns the gene GFAP and retinal ischemia.