We are grateful to Dr. Scott Kern for his generous gift of recombinant colon cancer cell lines RKO (FANCC parent), FCH3C12 (FANCC het +/−/−), FCE11C12 (FANCC null (−/−/−), DLD1 (BRCA2 parent), A9.A2 (BRCA2 het +/−) and A10.A3 (BRCA2 null −/−). Here, BRCA2 is linked to colonic neoplasm.