Consistent with these findings, FA-defective PDA lines Hs 766T (defective FANCG), PL11 (defective FANCC) and Capan-1 (defective BRCA2) showed hypersensitivity to DNA damaging agents such as mitomycin C (MMC) or cisplatin35. The gene discussed is FANCG; the disease is Patent ductus arteriosus.