These findings are consistent with the current evidence supporting the GABA hypothesis, in which reductions in the subpopulation of GABAergic interneurons expressing parvalbumin and the GABAAR β2 subunit have been reported in animal models of schizophrenia and in the post-mortem brains of schizophrenia patients18, 19, 20, 21, 22. Here, PVALB is linked to schizophrenia.