LARP4 and Familial prostate cancer: To study the effects of LARP4 on cell morphology, LARP4 was depleted by siRNA‐mediated knockdown in MDA‐MB‐231 breast cancer cells and PC3 prostate cancer cells, both of which migrate predominantly as single cells and do not express the epithelial cell‐cell adhesion molecule E‐cadherin [Neve et al., 2006; Valderrama et al., 2012].