Indeed, the largest epidemiological studies on this subject have identified hyperinsulinemia (or circulating C‐peptide or proinsulin) as a specific prognostic factor for cancer‐related mortality (Ma et al., 2008; Wolpin et al., 2009; Perseghin et al., 2012; Walraven et al., 2013). Here, INS is linked to hyperinsulinism.