Furthermore, CTGF overexpression has been associated with poor prognosis in several tumor types, including B-cell acute lymphoblastic leukemia (Boag et al. 2007; Sala-Torra et al. 2007), breast cancer (Chien et al. 2011), gastric cancer (Liu et al. 2008), glioma (Xie et al. 2004), melanoma (Hutchenreuther et al. 2015), pancreatic cancer (Bennewith et al. 2009) and prostate cancer (Yang et al. 2005). The gene discussed is CCN2; the disease is neoplasm.