In addition to neurotrophic BDNF, nerve growth factor (NGF), and glial cell line-derived neurotrophic factor (GDNF), as well as angiogenic VEGF and ANG1 identified in many other experiments, recent work identified the antiapoptotic activity of AD-MSCs, possibly by decreasing neuronal c-jun [116]. This evidence concerns the gene GDNF and Alzheimer disease.