EGFR and lung carcinoma: As loss of EGFR is known to induce cell death primarily via the autophagic mode, we treated different lung cancer cells (NCI-H2347, HCC827, and NCI-H1975 carrying wild-type, delE746-A750 and L858R/T790M mutant EGFR respectively) with erlotinib and tested the mode of cell death using markers of autophagic (LC-3B) cell death.