After 48 hours, the CXCR7 expression was higher in Ad5/CXCR7-transduced CAD-EOCs compared with Ad5/ GFP-transduced EOCs or non-transduced EOCs from CAD patients (p <0.05) (Fig 2A and 2B), which were examined by RT-qPCR and Western blot. Here, ACKR3 is linked to coronary artery disorder.